Custom GMP Pass Box for Cleanroom Material Transfer

Controlled material transfer for pharmaceutical, biotech and other GMP-regulated cleanrooms.

Custom GMP pass boxes provide controlled material transfer between clean and controlled areas while reducing the risk of cross-contamination. Designed for pharmaceutical, biotech, medical and other GMP-regulated facilities.

Key Benefits:

Stainless steel GMP construction
HEPA-filtered airflow available
Electronic door interlocking
PAO/DOP testing ports
Customized dimensions and configurations

REQUEST A QUOTE

How to Choose the Right GMP Pass Box?

The right GMP pass box depends on the required cleanliness level, material type, transfer direction, chamber size, and contamination-control requirements. Select the configuration based on your cleanroom process and project specifications.

GMP Pass Box Selection Guide

Requirement	Recommended Type	Main Purpose
Basic material transfer	Static Pass Box	Controlled transfer without active airflow
HEPA-filtered transfer	Dynamic Pass Box	Additional airborne contamination control
ISO 5 / Grade A protection	Laminar Flow Pass Box	Unidirectional HEPA-filtered airflow
Surface particle removal	Air Shower Pass Box	Air shower for transferred materials
Automated material transfer	Roller Conveyor Pass Box	Integration with material handling systems

Not Sure Which GMP Pass Box Fits Your Project?

Share your cleanroom layout, transfer requirements and chamber dimensions. Our engineers can recommend a suitable pass box configuration for your project.

GET A CUSTOM RECOMMENDATION →

Key Features of Custom GMP Pass Boxes

GMP Stainless Steel Construction

SUS304 / SUS316 stainless steel construction provides corrosion resistance, cleanability and durability for GMP-regulated environments.

Smooth Internal Surfaces

Continuous, smooth and easy-to-clean internal surfaces minimize particle accumulation and support hygienic material transfer.

Electronic Door Interlocking

Interlocked doors prevent both doors from being opened simultaneously, helping maintain controlled separation between cleanroom areas.

Optional HEPA Filtration

Dynamic configurations can integrate HEPA filtration and controlled airflow for applications requiring additional airborne particle control.

PAO/DOP Testing Ports

Built-in aerosol injection and sampling ports support HEPA filter integrity testing during commissioning and periodic qualification.

Differential Pressure Monitoring

Differential pressure monitoring provides real-time pressure indication for filter and airflow status monitoring.

GMP Pass Box Technical Specifications

Specification	Typical Configuration
Product Type	Custom GMP Pass Box
Construction	SUS304 / SUS316 stainless steel
Door Configuration	Single / Double door
Door Interlock	Mechanical / Electronic
Filtration	Optional HEPA filtration
Airflow	Static / Dynamic / Unidirectional airflow
Cleanliness	Project-dependent
Control System	Indicator / Touchscreen / PLC
Pressure Monitoring	Optional
Testing Ports	PAO/DOP ports available
Sterilization	UV lamp optional
Dimensions	Customized
Power Supply	AC220V / 50Hz or customized
Installation	Wall-mounted / Floor-mounted

GMP Pass Box Technical Drawing &Dimensions

Installation Requirements

Wall opening according to equipment dimensions
Sufficient service clearance
Power connection location
Door swing / access requirements
Filter replacement access for dynamic models

REQUEST CUSTOMIZED SPECIFICATION

GMP Pass Box Customization &Engineering Support

Every cleanroom project has different transfer routes, wall structures and contamination-control requirements. Flair provides customized GMP pass box design and engineering support from configuration selection to manufacturing.

Customization Options

Non-standard chamber dimensions
Single or double-door configurations
Wall-mounted or floor-mounted installation
HEPA filtration and airflow systems
Electronic interlocking
UV sterilization
HMI control systems
PAO/DOP testing ports

Request Customized Solution

Applications of GMP Pass Boxes

GMP pass boxes provide controlled material transfer between cleanrooms, controlled areas and adjacent production spaces, helping minimize unnecessary personnel movement and reduce the risk of cross-contamination.

Typical Application Areas

Pharmaceutical production
Biopharmaceutical manufacturing
Medical device manufacturing
Aseptic and sterile production
Controlled cleanroom areas

Typical Materials Transferred

Raw materials
Packaging components
Production components
Production tools
Cleanroom consumables

Pharmaceutical GMP Manufacturing

Controlled material transfer between classified areas in pharmaceutical production and GMP-regulated cleanrooms.

Biopharmaceutical Manufacturing

Supports controlled transfer of materials, components and process supplies in biopharmaceutical production areas.

Medical Device Manufacturing

Provides controlled material transfer between cleanroom production areas and supporting spaces for medical device manufacturing.

Aseptic & Sterile Manufacturing

Supports controlled material transfer in aseptic and sterile production areas where contamination control is critical.

FAQs

Find answers to frequently asked questions about our products. See the most common topics and more. Any other questions just feel free to contact us.

1. What is a GMP pass box?

A GMP pass box is a controlled material transfer unit used to transfer materials between cleanrooms or between areas with different cleanliness levels while minimizing cross-contamination.

It typically features interlocked doors, stainless steel construction, smooth internal surfaces and, depending on the application, HEPA filtration, airflow control, differential pressure monitoring, UV sterilization or other contamination-control options.

GMP pass boxes are commonly used in pharmaceutical manufacturing, biotechnology, medical device production and other controlled environments where material transfer must comply with GMP and cleanroom requirements.

2. What is the difference between a static and dynamic pass box?

The main difference is the airflow and filtration system.

A static GMP pass box does not continuously circulate or filter air inside the chamber. It is mainly used to provide a controlled physical transfer point between cleanroom areas. It is suitable when the required contamination-control level can be maintained through the surrounding cleanroom environment and proper transfer procedures.

A dynamic GMP pass box has a built-in fan and HEPA filtration system that continuously recirculates and filters air inside the chamber. It provides a higher level of airborne particle control and is suitable for applications requiring additional protection during material transfer.

Feature	Static GMP Pass Box	Dynamic GMP Pass Box
HEPA filtration	Optional / normally not included	Built-in
Air circulation	No	Yes
Particle control	Relies mainly on cleanroom environment	Active air filtration
Typical application	General cleanroom transfer	Higher contamination-control requirements
Power required	Usually no	Yes

For GMP projects, the appropriate type should be selected according to the cleanroom classification, material risk, transfer process and validation requirements.

3. What cleanroom class is a GMP pass box suitable for?

A GMP pass box can be configured for different cleanroom environments, but its suitability depends on the overall cleanroom design, airflow strategy, material-transfer procedure and required contamination-control level.

For pharmaceutical and biotech applications, pass boxes are commonly integrated into GMP-regulated cleanrooms and controlled material transfer routes.

For higher-containment or higher-cleanliness applications, a dynamic GMP pass box can be equipped with HEPA filtration, controlled airflow, differential pressure monitoring and other contamination-control features.

The final configuration should be determined based on the project’s required cleanroom classification, process requirements and applicable GMP/cleanroom standards rather than selecting a pass box based on cleanroom class alone.

4. Can GMP pass boxes be customized for pharmaceutical cleanroom projects?

Yes. GMP pass boxes are commonly customized according to the cleanroom layout, wall construction, material size, transfer method and project specifications.

Customization options can include:

Chamber dimensions and door opening size
SUS304 or SUS316 stainless steel construction
Single-door or double-door configurations
Static or dynamic airflow design
HEPA filtration system
Electronic door interlocking
Differential pressure monitoring
UV sterilization
DOP/PAO testing ports
HMI or PLC control systems
Different installation configurations
Special transfer openings or conveyor integration

For EPC and engineering projects, the pass box can also be supplied according to approved drawings, technical specifications and cleanroom layout requirements.

5. How is a GMP pass box installed and maintained?

A GMP pass box can be installed as a wall-mounted, floor-mounted or integrated cleanroom-wall system, depending on the project design.

Before installation, the required wall opening, equipment dimensions, service clearance, electrical connection and maintenance access should be confirmed.

For dynamic GMP pass boxes, sufficient service-side clearance should be provided for HEPA filter replacement, fan maintenance and inspection.

After installation, the pass box should be checked according to the project’s commissioning and validation requirements. Depending on the configuration, testing may include:

The exact testing and qualification protocol should follow the project URS, commissioning requirements and applicable GMP/cleanroom procedures.

6. Can you provide a customized GMP pass box for EPC and cleanroom projects?

Yes. We provide custom GMP pass box solutions for pharmaceutical, biotechnology, medical device and other controlled-environment projects.

For EPC contractors, cleanroom contractors and engineering companies, we can support the project from technical specification and equipment selection through engineering design and manufacturing.

Typical project support includes:

Customized pass box dimensions and configurations
Technical drawings and equipment specifications
Material and component selection
Cleanroom wall integration
Door interlock and control system design
HEPA filtration and airflow configuration
Factory inspection and functional testing
Project-based manufacturing
Documentation support for installation and commissioning

If you have the cleanroom classification, wall thickness, material dimensions, transfer direction and required pass box quantity, these details can be used to determine the appropriate configuration and prepare a customized quotation.

Fan Filter Unit (FFU)

Air Shower

Pass Box

Clean Booth

FFU Air Purifier

Laminar Flow Hood

Restricted Access Barrier System (RABS)

Sampling /Weighing /Dispensing Booth

Laminar Flow Clean Bench/Cabinet

Laminar Flow Trolley/Cart(LFT)

Ducted Ceiling Filter Module

Compact Filter

V-bank Filter

Mini-pleat HEPA /ULPA Filter

Pleated Air Filter

Gel HEPA Filter

Pre Filter

Pocket/Bag Filter